Oral solid self-nanoemulsifying drug delivery systems of candesartan citexetil: formulation, characterization and in vitro drug release studies

AAPS Open

Table 11 Release kinetics of candesartan cilexetil form SSNEDDS-5 in different media

F-code	Zero order (R²)	First order (R²)	Higuchi (R²)	Hixson Crowell (R²)	Korsmeyer and Peppas
F-code	Zero order (R²)	First order (R²)	Higuchi (R²)	Hixson Crowell (R²)	R²	n	Release mechanism
SSNEDDS-5 in 0.1 N HCl (pH 1.2)	0.9909	0.7158	0.9579	0.7776	0.9522	1.5490	Supercase II Transport
SSNEDDS-5 in phosphate buffer (pH 6.8)	0.9885	0.7089	0.9618	0.7708	0.9483	1.5485	Supercase II Transport
SSNEDDS-5 in water	0.9849	0.7142	0.9610	0.7745	0.9527	1.5558	Supercase II Transport