Oral nanoemulsions of candesartan cilexetil: formulation, characterization and in vitro drug release studies

AAPS Open

Table 8 Release kinetics study of candesartan cilexetil form nanoemulsions

F-code	Zero order (R²)	First order (R²)	Higuchi (R²)	Korsmeyer and Peppas
F-code	Zero order (R²)	First order (R²)	Higuchi (R²)	R²	n	Release mechanism
NE-1	0.9939	0.6995	0.8857	0.9675	1.3013	Supercase II transport
NE-2	0.9965	0.6420	0.9344	0.9549	1.2658	Supercase II transport
NE-3	0.9853	0.5978	0.9586	0.9392	1.2949	Supercase II transport
NE-4	0.9895	0.6538	0.9518	0.9400	1.4131	Supercase II transport
NE-5	0.9801	0.5737	0.9701	0.9253	1.2888	Supercase II transport
NE-6	0.9893	0.6409	0.9247	0.9504	1.2765	Supercase II transport
NE-7	0.9863	0.6775	0.9369	0.9708	1.2271	Supercase II transport
NE-8	0.9957	0.6597	0.9132	0.9539	1.2432	Supercase II transport
Marketed	0.9838	0.8426	0.9151	0.9707	1.0408	Supercase II transport