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Fig. 7 | AAPS Open

Fig. 7

From: Nano-formulations composed of cell membrane-specific cellular lipid extracts derived from target cells: physicochemical characterization and in vitro evaluation using cellular models of breast carcinoma

Fig. 7

Isolation of lipid extracts from target cells in preparation of CLENs. The schematic shows the process for preparing CLENs from isolation of the chloroform-soluble fraction which corresponds to the lipid extract phase mixture. The inclusion of cholesterol and DPPE-PEG5000 in CLENs improved drug incorporation, stability, cellular uptake, and cytotoxicity among other formulation properties

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