Fig. 14From: Antibody-drug conjugates: integrated bioanalytical and biodisposition assessments in lead optimization and selectionImmunohistochemical analysis of cellular disposition of DyLight 650-labeled Pep-ADC (a and b) and Dylight 650-labeled unconjugated mAb3 (c and d). Tissue sections were stained with anti-DyLight 650 dye specific antibody. Asterisk (*) represents Pep-ADC localized to pancreatic Islets of Langerhans at Day 1. Arrowheads show labeling of capillaries with both antibodiesBack to article page