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Fig. 4 | AAPS Open

Fig. 4

From: Antibody-drug conjugates: integrated bioanalytical and biodisposition assessments in lead optimization and selection

Fig. 4

Anti-CD74-Phos-Bud-interacting proteins in C57BL/6 J plasma. To determine any off-target protein binding, Anti-CD74-Phos-Bud was incubated in C57BL/6 J mouse plasma for 14 days at 37 °C and retrieved by pull-down. Pulled-down products were digested with trypsin and analyzed by LC-MS/MS for peptide mapping. Data represent the results of a single incubation at each time point

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