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Table 1 PK parameters following IV administration of anti-CD74 to C57BL/6 J mice

From: Antibody-drug conjugates: integrated bioanalytical and biodisposition assessments in lead optimization and selection

Dose
(mg/kg) 		t1/2
(day) 		Cmax
(μg/mL) 		CL
(mL/day/kg) 		Vss
(mL/kg) 		AUC0-INF
(day*μg/mL)
10 3.75 90.0 195 589 51.4
3 3.42 27.8 70.3 295 42.7
1 3.90 12.0 39.8 197 25.2
0.3 3.97 2.72 31.5 170 9.52
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