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Fig. 2 | AAPS Open

Fig. 2

From: A bridging assay for detection and characterization of anti-drug antibodies to dostarlimab, a new anti-PD-1 therapeutic monoclonal antibody

Fig. 2

Plot of percent inhibition versus log S/N ratio values for all serum samples in study. The vertical reference line is the 95% parametric screening cut point of 0.045, which corresponds to an S/N ratio value of 1.109. The horizontal reference line is the 99% parametric confirmation cut point of 40.7. PINH is calculated as (signal sample without drug—signal sample with 405 μg/mL drug)/signal sample without drug × 100%

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