Skip to main content
AAPS Open
Fig. 4 | AAPS Open

Fig. 4

From: Strategies to stabilize dalbavancin in aqueous solutions: Section 4—identification of heat degradation products in 2-hydroxypropyl-β-cyclodextrin and divalent metal ion solutions at pH 4.5 and 7.0

Fig. 4

Extracted ion chromatograms of a the ion at m/z [M + H]+  = 1817.65 Da from heat-stressed dalbavancin in acetate buffer, reproducing the LC peak corresponding to compound 5 (dalbavancin). b The ion at m/z [M + H]+  = 1460.35 Da from acetate buffer, reproducing the LC peak corresponding to compound 1 (MAG). c The ions at m/z [M + H].+  = 1817.65 Da from heat-stressed dalbavancin in phosphate buffer with 2HPβCD, reproducing the LC peaks corresponding to compounds 4a (DB-R2) and 5 (dalbavancin)

Back to article page