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Table 1 Composition of 20 mg/mL (11 mM) dalbavancin liquid formulations in 10 mM acetate buffer (pH 4.5) and 10 mM phosphate buffer (pH 7.0)

From: Strategies to stabilize dalbavancin in aqueous solutions: Section 4—identification of heat degradation products in 2-hydroxypropyl-β-cyclodextrin and divalent metal ion solutions at pH 4.5 and 7.0

Dalbavancin solution ID	Metal ion	2HPβCD
AcB10	None	None
AcB10Ca10	Ca²⁺ 10 mM	None
AcB10Mg2	Mg²⁺ 2 mM	None
AcB10Zn2	Zn²⁺ 2 mM	None
AcB10Cyclod55	None	55 mM
AcB10Ca10Cyclod55	Ca²⁺ 10 mM	55 mM
Phosp10^a	None	None
Phosp10Cyclod110	None	110 mM
Phosp10Mg50Cyclod110	Mg²⁺ 50 mM	110 mM

^aDalbavancin precipitated in phosphate buffer solution without 2HPβCD

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