Table 2 Advantages and disadvantages of different emulsomal technique
Technique | Benefits | Shortages | Ref |
|---|---|---|---|
Thin film hydration method | • Higher entrapment of drug due to its ability to form multilamellar vesicles | • Produce large vesicles | Varshosaz et al. 2019) |
Ethanol injection method | • Easy and reproducible • Small particle size was obtained | • Ethanol removal is very difficult | Gouda et al. 2021) |
High-pressure extrusion method | • Rapid • Reproducible • Variety of size range | • This technique is unsuitable for heat sensitive materials and large-scale preparations, so the process must be heat controlled | Ucisik et al. 2013a) |