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Table 5 Formulations prepared with the excipients of system D obtained from an augmented lattice simplex experimental design

From: Self-microemulsifying system of an ethanolic extract of Heliopsis longipes root for enhanced solubility and release of affinin

Formulation D

Transcutol®

Tween® 80/PG(1:1)

Labrasol®

Droplet size (nm)

1

0.60

0.10

0.30

69 ± 2.5

2

0.57

0.12

0.31

78 ± 4.4

3a

0.55

0.10

0.35

82 ± 2.6

4

0.55

0.15

0.30

94 ± 8.0

5

0.54

0.13

0.33

73 ± 4.5

6

0.52

0.12

0.36

76 ± 13.1

7

0.52

0.16

0.32

85 ± 7.8

8

0.50

0.10

0.40

78 ± 4.7

9

0.50

0.15

0.35

97 ± 5.6

10

0.50

0.20

0.30

94 ± 9.0

  1. aHL-SMDS optimal formultion