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Table 2 Effect of alcohol on pharmacokinetic parameters of EMBEDA (fasted state) (data from reference (Johnson et al. 2012))

From: A review of in vivo and in vitro aspects of alcohol-induced dose dumping

Parameter

Ratio 4

Ratio 20

Ratio 40

Cmax

1.03

1.08

2.00

AUC0-t

1.01

0.98

0.97

AUC∞

0.97

0.94

1.10

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