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Table 4 DA/N values of tramadol from Tridural™ Tablets, Ultram®ER Tablets, and T-long® Capsules after 4 h in 20 and 40% ethanolic media (data from reference (Traynor et al. 2008))

From: A review of in vivo and in vitro aspects of alcohol-induced dose dumping

Formulation

DA/N value (20% ethanol)

DA/N value (40% ethanol)

Tridural™ Tablets

−27.55

−20.77

Ultram®ER Tablets

37.09

214.21

T-long® Capsules

73.81

113.68