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Table 4 Impact of solubility on mean dissolution time of inhaled corticosteroids

From: Scope and relevance of a pulmonary biopharmaceutical classification system AAPS/FDA/USP Workshop March 16-17th, 2015 in Baltimore, MD

Drug CS (μg/ml) Do Mean Dissolution Time (hr)
Fluticasone propionate 0.14 27 >8
Beclomethasone dipropionate 0.13 15 >5
Budesonide 16 0.375 ~0.1
Flunisolide 140 0.01 <0.03