Fig. 5
From: Solid form changes during drug development: good, bad, and ugly case studies
AUC (a) and Cmax (b) curves for indinavir as a function of the administered single-dose; AUC and Cmax values were normalized to a 1-mg dose. ○ sulfate salt fasted state; ● sulfate salt following a high-fat meal; ☆ sulfate salt following low fat meal; □ free-base capsules fasted state; ▪ free base capsules following a high-fat meal; ♦ free base oral suspension fasted state (used with permission from Ref (Yeh et al. 1998))