Excipient | CYP3A | P-gp |
---|---|---|
C8–C20 fatty acid glycerol and PEG esters: Cremophor EL and RH40, Solutol HS-15, Labrasol, Softigen 767, Aconnon E | - | + |
Sodium Caprate | - | + |
Polysorbates : Tween 80, Tween 20 | + | + |
Sucrose esters : sucrose monolaurate | - | + |
Tocol esters : TPGS | - | + |
PEG 300/400 | - | + |
Triton X-100 | - | + |
Pluronic block copolymer (Pluronic F68) | + | + |
Amphiphilic diblock copolymers (Me-PEG-b-PCL) | - | + |
Peppermint Oil | + | - |