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Table 1 M4KRC fourth tier candidate API molecules

From: Development of an algorithm to identify mass production candidate molecules to develop children’s oral medicines: a North American perspective

Generic name

BCPA listed?

Injection?

Non-scheduled?

Oral adult market?

Established adult indication?

Off patent?

Dose form in UK?

Baclofen

1

1

1

1

1

1

Yesa

Warfarin

1

1

1

1

1

1

Yesb

Sildenafil

1

1

1

1

1

1

Yesc

L-thyroxine

1

1-lyo

1

1

1

1

Yesd

  1. aAvailable as 5 mg/mL oral solution at http://medicines.org.uk/emc/medicine/14939/SPC/Lyflex+5mg+5ml+Oral+Solution/
  2. bAvailable as 1 mg/mL oral suspension at http://medicines.org.uk/emc/medicine/23933/SPC/Warfarin+Sodium+1mg+1ml+Oral+Suspension/
  3. cAvailable as 10 mg/mL suspension powder at http://medicines.org.uk/emc/medicine/27153/SPC/Revatio+10+mg+ml+powder+for+oral+suspension/
  4. dAvailable as 5 microgram/mL and 20 microgram/mL at http://medicines.org.uk/emc/medicine/26562/SPC/Eltroxin+25micrograms+per+5ml+Oral+Solution/
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