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Table 3 Regression coefficients for data fitted to the modified Arrhenius equation (Eqs. 2 and 3) and the Dimensionless equation (Eq. 4) for the two active ingredients

From: Prediction of the changes in drug dissolution from an immediate-release tablet containing two active pharmaceutical ingredients using an accelerated stability assessment program (ASAPprime®)

API

ln A

Ea (kcal/mol)

C (x 10-4)

B (x 10-2)

R2

(SD)

(SD)

(SD x 10-4)

(SD x 10-2)

1

73.8 (5.7)

50.0 (3.9)

2.52 (0.02)

5.3 (0.8)

0.937

2

71.4 (9.7)

51.0 (6.6)

2.58 (0.03)

10.4 (1.9)

0.954

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