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Table 4 Predicted and observed water content of tablets packaged in Aclar® foil blisters at different storage conditions (Temperature (T) and Relative Humidity (RH))

From: Prediction of the changes in drug dissolution from an immediate-release tablet containing two active pharmaceutical ingredients using an accelerated stability assessment program (ASAPprime®)

Study

Storage Conditions

Water Content (% w/w)

T (°C)

RH (%)

Time (months)

Initial

Predicted

Observed

1

30

75

6

2.1

2.4

2.2

40

75

6

2.8

2.7

25

60

6

2.3

2.0

2

25

60

3

2.4

2.5

2.4

30

65

3

2.5

2.3

40

75

3

2.8

2.7

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