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Table 3 Ratios and 90% Geometric Confidence Intervals

From: A randomized, open-label study assessing the bioequivalence of two formulations of Fingolimod 0.5 mg in healthy subjects

Parameter Treatment Comparisons Ratioa 90% Geometric CIb Intra-subject CV Inter-subject CV
Lower Upper
AUC0–72 Test vs Reference 99.15% 95.88% 102.52% 4.53% 9.96%
Cmax Test vs Reference 98.58% 94.61% 102.72% 5.56% 11.35%
  1. AUC 0–72 area under the concentration–time curve from time 0 to hour 72, C max maximum concentration, CV coefficient of variation
  2. aCalculated using least-squares means according to the formula: e(difference) × 100
  3. b90% geometric confidence interval (CI) using ln-transformed data