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Table 3 Characterization and evaluation of 4 T1 CLENs loading efficiency

From: Nano-formulations composed of cell membrane-specific cellular lipid extracts derived from target cells: physicochemical characterization and in vitro evaluation using cellular models of breast carcinoma

# Nanoliposomes mol% Particle Size (nm) Z-Potential (mV) Dox Incorporation Efficiency %
1 4 T1/chol 100/0 131 ± 6.5 − 14 ± 0.4 63 ± 1.3
2 4 T1/ chol 90/10 184 ± 0.4 − 20 ± 1.2 64 ± 1.9
3 4 T1/ chol 75/25 239 ± 4.3 −18 ± 2.50 86 ± 0.9
4 4 T1/ chol 50/50 282 ± 0.3 −20 ± 2.50 44 ± 0.9
5 4 T1/ chol /PEG-5000 73/25/2 180 ± 5.2 −10 ± 1.2 81 ± 1.5
6 4 T1/ chol /PEG-5000 70/25/5 179 ± 0.2 −13 ± 1.5 93 ± 0.9
7 4 T1/ chol /PEG-5000 65/25/10 290 ± 0.4 −10 ± 1.7 41 ± 0.3
8 DoxilLP 45/50/5 168 ± 0.6 −13 ± 1.5 95 ± 1.1