Fig. 12

The concentration time profiles of Pep-ADC and unconjugated mAb3. Plasma was collected at indicated time points over 14 days following a single 3 mg/kg IV administration of DyLight 650-labeled Pep-ADC or DyLight 650-labeled unconjugated mAb3 in normal C57BL/6 J mice, and the concentrations were determined by fluorescence emission-linked assays. Data plotted are mean from two mice per time point. Error bars correspond to the range. Error bars smaller than the symbols are not plotted