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Fig. 1 | AAPS Open

Fig. 1

From: Similarity assessment of quality attributes of biological medicines: the calculation of operating characteristics to compare different statistical approaches

Fig. 1

Definition of the statistical equivalence region: The dark grey region is the defined true similarity region and indicates those combinations of SD ratio and difference in mean where the test population is within the reference population. The population width is described by μ ± 3σ, which translates into a triangle with the corners of SD ratio and difference in means of (0/0, 1/0, 0/3). The light grey region is the statistical non-equivalence (false similarity) region indicating where the test population is not considered to be within the reference population

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