Table 4 Predicted results and confidence intervals for the selected responses of the optimized method
Response | Goal | Predicted result | Desirability | − 2 Sigma conf. limit | + 2 Sigma conf. limit |
|---|---|---|---|---|---|
No. of peaks | Maximize | 8.0 | 1.0000 | 6.3 | 10.5 |
No. of peaks ≥ 1.5 — USP resolution | Maximize | 6.2 | 1.0000 | 4.8 | 9.5 |
Max peak 1 – USP plate count | Maximize | 20,313 | 1.0000 | 17,560 | 23,067 |
Max peak 1 — USP plate count — Cpk | Maximize | 2.01 | 1.0000 | 1.78 | 2.24 |
No. of peaks ≥ 1.5 — USP resolution — Cpk | Maximize | 3.59 | 1.0000 | 3.54 | 3.63 |