Fig. 3From: Tritium labeling of antisense oligonucleotides via different conjugation agentsConcentration-dependent target reduction in mouse hepatocytes (in vitro) treated with NSP and maleimide-tagged naked ASOs and their untagged counterpart. Malat1 RNA levels were assessed after A 24 h and B 72 h. C Malat1 RNA levels of GalNAc-conjugated oligonucleotides compared with naked-Malat1 and negative-control ASO after 24 h (mean and SD, n=3)Back to article page