Fig. 4From: Tritium labeling of antisense oligonucleotides via different conjugation agentsHPLC measurements (AIF, normalized) of naked ASO constructs from the MetID study. From the top: ASO 1 (untagged), ASO 2 (NSP), ASO 3 (NMM), and ASO 4 (NEM). A Reference compounds. B After 72 h incubation in primary mouse hepatocytes. (*) Arrow indicates the undesired degradation product of hydrolysis, which results to the loss of the tagBack to article page