Table 3 Most abundant metabolites observed in urine of mice from 0 to 24 h after a single dose of [3H]-NEM-labeled ASOs 7 and 8. Capital letters in the oligonucleotide sequence describe LNA-modified nucleosides, and small letters describe DNA nucleosides. n.d. not detectable
From: Tritium labeling of antisense oligonucleotides via different conjugation agents
