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Table 7 Ex vivo permeation studies of OZ (gamma oryzanol) gel and OZ niosomal gel

From: Gamma oryzanol niosomal gel for skin cancer: formulation and optimization using quality by design (QbD) approach

 

Drug content (%)

% Drug diffused after 60 min

% Drug diffused after 120 min

% Drug in donor compartment

% Drug retained after 120 min

OZ gel

96.5 ± 1.5

5.8 ± 0.5

7.7 ± 1.2

75.2 ± 4.3

13.60 ± 2.1

OZ niosomal gel

99.7 ± 2.1

17.3 ± 0.9

25 .1 ± 2.7

3.2 ± 0.1

71.17 ± 3.6