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Table 8 Stability results of OZ (gamma oryzanol) niosomal gel

From: Gamma oryzanol niosomal gel for skin cancer: formulation and optimization using quality by design (QbD) approach

Time point

Viscosity (cPs)

pH

Spreadability

% Drug diffused after 60 min

% Drug diffused after 120 min

% Drug in donor compartment

% Drug retained after 120 min

Initial

8489

7.3 ± 0.1

Very good

17.3 ± 0.9

25 .1 ± 2.7

3.2 ± 0.1

71.2 ± 3.6

3 month

7444

7.1 ± 0.1

Good

15.7 ± 1.6

23.8 ± 6.1

3.4 ± 0.9

72.5 ± 4.3