Fig. 4
From: An industrial case study: QbD to accelerate time-to-market of a drug product
Criticality assessment of the unit operations (UOs) using iRISKTM Cause-Effect Matrix. The risk of a given UO (in rows) affecting a given product’s CQA (in columns) was classified as low (score of 1), medium (score of 3), and high (score of 9). Due to confidentiality reasons, not all of the CQAs are shown. Given their higher overall score, operations UO2 and UO6 (highlighted) were identified as the top 2 UOs potentially affecting the product’s Critical Quality Attributes (CQAs)