Table 1 Impurity limits and GC-MS conditions of active ingredients, impurities, and internal standards
Compound | Conc. limit (ppm) | Ret. time (min) | Quantifier ion (m/z) | Qualifier ion (m/z) |
|---|---|---|---|---|
Ethanol | 1.82 | 45 | 31 | |
Isopropanol | 2.28 | 45 | 29 | |
Acetaldehyde | 50 | 1.28 | 43 | 29 |
Methanol | 630 | 1.34 | 31 | 29 |
Benzene | 2 | 4.13 | 78.1 | 51 |
Acetal | 50 | 4.89 | 73.1 | 45.1 |
Acetone | 4400 | 2.13 | 58.1 | 43 |
1-Propanol | 1000 | 3.12 | 31.1 | 59.1 |
Ethyl Acetate | 2200 | 3.54 | 61.1 | 43.1 |
2-Butanol | 6200 | 3.64 | 59.1 | 45.1 |
Isobutanol | 21700 | 4.01 | 31.1 | 43.1 |
1-Butanol | 1000 | 4.52 | 56.1 | 41.1 |
3-Methyl-1-Butanol | 4100 | 5.38 | 70.1 | 55.1 |
Amyl Alcohol | 4100 | 5.72 | 70.1 | 55.1 |
Acetone-d6 | 2.10 | 64.1 | 46 | |
Cyclohexane | 3.93 | 84.1 | 56.1 |