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Fig. 3 | AAPS Open

Fig. 3

From: Pharmacokinetic and pharmacodynamic analyses of terlipressin in patients with hepatorenal syndrome

Fig. 3

Visual predictive check: model-predicted and observed plasma concentrations of terlipressin and L-VP in patients with HRS. Blue circle markers represent observed PK data; solid red line represents the median observed values; solid red areas indicate the model-predicted 90% confidence interval for the median. The 2.5th and 97.5th percentiles of observed data are presented with dashed red lines, and the blue solid areas represent the model-predicted 90% confidence intervals for the corresponding percentiles. HRS, hepatorenal syndrome; L-VP, lysine-vasopressin; PK, pharmacokinetic

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