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Table 3 Inclusion thermodynamic parameters at different pH

From: Molecular docking assisted exploration on solubilization of poorly soluble drug remdesivir in sulfobutyl ether-tycyclodextrin

pH

ΔG (KJ·mol-1 )

ΔH (J·mol-1 )

ΔS (J· mol-1.K-1)

298K

310K

318K

298~318 K

298~318K

1.5

-12.43

-13.50

-12.35

-11039.7

5.58

1.7

-10.31

-11.46

-11.16

3809.7

47.91

2.0

- 9.44

- 9.45

-10.36

3037.4

41.43

3.0

- 10.74

- 10.23

-11.23

-5271.7

17.70

3.5

-10.73

-13.21

- 11.68

7810.4

63.76

4.0

-13.40

-14.63

- 12.85

-18071.0

-14.40