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Table 4 Effect of feeding molar ratio on solubility of RDV (pH=1.7, 25 °C)

From: Molecular docking assisted exploration on solubilization of poorly soluble drug remdesivir in sulfobutyl ether-tycyclodextrin

Feeding molar ratio of RDV / SBE-β-CD (actual value) S / (mM) Determined molar ratio of RDV / SBE-β-CD in solution
1/16 (0.064) 5.680 0.061
1/10 (0.103) 9.205 0.099
1/8 (0.119) 10.741 0.116
1/7 (0.148) 13.402 0.145
1/5 (0.193) 14.264 0.154
1/4 (0.256) 22.916 0.248
1/2 (0.477) 24.645 0.266