Skip to main content

Table 4 Effect of feeding molar ratio on solubility of RDV (pH=1.7, 25 °C)

From: Molecular docking assisted exploration on solubilization of poorly soluble drug remdesivir in sulfobutyl ether-tycyclodextrin

Feeding molar ratio of RDV / SBE-β-CD (actual value)

S / (mM)

Determined molar ratio of RDV / SBE-β-CD in solution

1/16 (0.064)

5.680

0.061

1/10 (0.103)

9.205

0.099

1/8 (0.119)

10.741

0.116

1/7 (0.148)

13.402

0.145

1/5 (0.193)

14.264

0.154

1/4 (0.256)

22.916

0.248

1/2 (0.477)

24.645

0.266