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Fig. 2 | AAPS Open

Fig. 2

From: Results from in vitro and in vivo studies evaluating the bioavailability, effects of food, and administration as crushed tablet suspension on vericiguat pharmacokinetics

Fig. 2

Dissolution of vericiguat 10 mg as an intact tablet, crushed tablet suspension immediately after preparation, and as a crushed tablet suspension 4 h after preparation (n = 12) in 900 mL of A 0.01 M HCl pH2, B acetate buffer pH 4.5, and C phosphate buffer pH 6.8, at 37°C at 75 rpm. 95% confidence interval bars are contained within the data symbols

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