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Table 2 Breakdown of high-fat, high-calorie and low-fat, low-calorie meals

From: Results from in vitro and in vivo studies evaluating the bioavailability, effects of food, and administration as crushed tablet suspension on vericiguat pharmacokinetics

 

High-fat, high-calorie meal

Low-fat, low-calorie meal

Fat content, g (kcal)

63.5 (584.2)

24.8 (222)

Protein content, g (kcal)

42 (176.4)

6 (25)

Carbohydrate content, g (kcal)

67 (281.4)

36.5 (160)

Total calories (kcal)

1042

407

  1. Example of high-fat, high-calorie meal: two large eggs fried in 10 g butter, two slices of fried ham, two slices of toast, 20 g butter, pan-fried potatoes, milk with 3.5% fat and 100–150 mL decaffeinated coffee
  2. Example of a low-fat/low-calorie meal: two slices of toasted white bread with butter and jam, cheese (45% fat) and 200 mL of tea with a cube of sugar (approximately 3 g)