Skip to main content
Fig. 11 | AAPS Open

Fig. 11

From: Formulation mitigations for particle formation induced by enzymatic hydrolysis of polysorbate 20 in protein-based drug products: insights from a full-factorial longitudinal study

Fig. 11

Correlations between intact [PS20], [LA], [MA], [PA], and [SA] in mAb X DP formulations stored at 5 °C. Formulations shown here contain the same initial [PS20] (0.04% w/v) paired with unique combinations of [mAb] and pH. Intact PS20 was quantified by HPLC-ELSD; FFAs were quantified by LC–MS. Correlation coefficient (r) values are shown within the scatterplot matrix

Back to article page