Skip to main content

Table 1 Average statistical power over all effects to detect an effect within 2 or 3 standard deviations from the set point. Note that those values represent the worst case that assumes a full model, i.e., a model that includes all quadratic and interaction effects

From: Incorporating random effects in biopharmaceutical control strategies

UO

Power for 2 SD

Power for 3 SD

Runs DoE/OFAT

RE levels

Significant effects

Responses

UO 1

0.91

0.99

24/6

3

16

22

UO 2

1.00

1.00

27/24

4-5

30

20

UO 3

0.95

1.00

17/5

5

10

14

UO 4

0.71

0.93

18/3

6

10

11

UO 5

0.94

1.00

21/3

5

15

17

UO 6

0.99

1.00

42/11

3

36

13

UO 7

0.82

0.96

0/6

5

3

11

UO 8

0.89

0.98

0/13

5

8

15