Dissolution profile evaluation of selected brands of amoxicillin-clavulanate potassium 625 mg tablets retailed in Hawassa town, Sidama Regional State, Ethiopia

AAPS Open

Table 6 The model dependent results for the seven brands of tablets contained amoxicillin-clavulanate potassium 625 mg tablets (500 mg/125 mg)

Brands code	Amoxicillin					Clavulanic acid potassium salts
Brands code	f1	f2	DE%	Difference DE	MDT	F1	F2	DE%	Difference DE	MDT
AC001^a	-	-	87.6	0	7.1	-	-	79.9	0	9.8
AC002	4.86	51.05	84.1	3.5	6.7	0.23	98.4	80.3	− 0.4	6.4
AC003	6.55	44.58	90.23	-2.63	2.3	7.06	45.05	74.1	5.8	1.02
AC004	8.75	38.3	77.9	9.7	1.3	8.2	41.75	72.9	7	8.7
AC005	5.03	85.102	83.4	4.2	6.7	0.61	91.63	78.9	1	1.03
AC006	0.13	99.4	87.1	0.5	6.8	3.27	61.48	75.9	4	9.8
AC007	7.52	41.56	81.4	6.2	8.8	2.48	67.3	80.3	− 0.4	8.4

^aAC001 innovator product, DE dissolution efficiency, MDT mean dissolution time, Difference of DE innovator- tested brands